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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BECN1
All Species:
41.52
Human Site:
S346
Identified Species:
60.89
UniProt:
Q14457
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14457
NP_003757.1
450
51896
S346
L
E
S
L
T
D
K
S
K
E
L
P
L
Y
C
Chimpanzee
Pan troglodytes
XP_511522
450
51866
S346
L
E
S
L
T
D
K
S
K
E
L
P
L
Y
C
Rhesus Macaque
Macaca mulatta
XP_001111932
450
51890
S346
L
E
S
L
T
D
K
S
K
E
L
P
L
Y
C
Dog
Lupus familis
XP_537634
362
42279
D278
F
F
W
D
N
K
F
D
H
A
M
V
A
F
L
Cat
Felis silvestris
Mouse
Mus musculus
O88597
448
51515
S344
L
E
S
L
T
D
K
S
K
E
L
P
L
Y
C
Rat
Rattus norvegicus
Q91XJ1
448
51538
S344
L
E
S
L
T
D
K
S
K
E
L
P
L
Y
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514527
394
45783
F309
R
F
F
W
D
N
K
F
D
H
A
M
V
A
F
Chicken
Gallus gallus
Q5ZKS6
447
51416
S343
L
E
S
L
T
D
K
S
K
E
L
P
L
Y
C
Frog
Xenopus laevis
Q6GP52
445
51275
S341
L
E
S
L
T
D
K
S
K
E
L
P
L
Y
C
Zebra Danio
Brachydanio rerio
P13104
284
32704
T199
E
L
E
E
E
L
K
T
V
T
N
N
M
K
S
Tiger Blowfish
Takifugu rubipres
NP_001032963
447
51199
S343
L
E
S
L
T
D
K
S
K
E
L
P
L
Y
C
Fruit Fly
Dros. melanogaster
Q9VCE1
422
48852
R322
V
E
V
L
G
E
N
R
E
L
P
L
Y
G
S
Honey Bee
Apis mellifera
XP_392365
430
49618
R326
I
E
A
L
D
Q
H
R
E
L
P
L
Y
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786368
415
47747
S315
L
E
S
L
T
D
K
S
K
Q
L
P
L
H
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M367
517
58486
T384
I
V
D
S
N
N
E
T
Y
E
L
F
G
P
V
Baker's Yeast
Sacchar. cerevisiae
Q02948
557
63242
T451
L
E
I
I
S
E
I
T
R
Q
L
S
T
I
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.7
78.8
N.A.
97.3
97.3
N.A.
76.8
91.7
88.6
20
81.1
49.1
56.4
N.A.
57.5
Protein Similarity:
100
99.7
99.7
79.5
N.A.
98
98.2
N.A.
81.5
94.6
94.8
36.4
89.5
67.7
69.3
N.A.
71.5
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
6.6
100
100
6.6
100
13.3
13.3
N.A.
80
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
20
100
100
20
100
33.3
33.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
0
7
7
0
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% C
% Asp:
0
0
7
7
13
57
0
7
7
0
0
0
0
0
0
% D
% Glu:
7
75
7
7
7
13
7
0
13
57
0
0
0
0
0
% E
% Phe:
7
13
7
0
0
0
7
7
0
0
0
7
0
7
7
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
0
7
13
7
% G
% His:
0
0
0
0
0
0
7
0
7
7
0
0
0
7
0
% H
% Ile:
13
0
7
7
0
0
7
0
0
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
0
7
69
0
57
0
0
0
0
7
0
% K
% Leu:
63
7
0
69
0
7
0
0
0
13
69
13
57
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
7
7
0
0
% M
% Asn:
0
0
0
0
13
13
7
0
0
0
7
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
13
57
0
7
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
13
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
13
7
0
0
0
0
0
0
% R
% Ser:
0
0
57
7
7
0
0
57
0
0
0
7
0
0
19
% S
% Thr:
0
0
0
0
57
0
0
19
0
7
0
0
7
0
0
% T
% Val:
7
7
7
0
0
0
0
0
7
0
0
7
7
0
7
% V
% Trp:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
13
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _